Foundational guide
FOXO4-DRI Price: Cost Per Milligram of What, Exactly
Per-milligram pricing assumes the labelled mass is the delivered mass. For this compound the vendor's own certificates put that assumption 17% out on one batch and 14% out on the other.
The FOXO4-DRI price is $67.00 for a 10 mg vial with the discount applied. Converting that to cost per milligram requires knowing how many milligrams arrived, and that is the figure this market almost never measures.
Where it has been measured for this product, it did not match the label in either direction.
Supplier publishing lot-level data
FOXO4-DRI, Ascension Peptides
Two independent laboratories have certified this product, though on different batches. The code below halves the listed price on the vial.
The two published certificates cover different lots and disagree on fill: Kovera Labs assays batch 55-05260628 at 11.41 mg, MZ Biolabs assays lot 55-01260229 at 8.30 mg, both against a 10 mg label, moving the real figure between $5.87/mg and $8.07/mg. Endotoxin and sterility screens appear on the Kovera lot only, so testing scope here is a batch property rather than a product feature. The vendor spells the product FOX04 with a zero, including in the link.
- Kovera Labs and MZ Biolabs certificates, different lots
- Carriage free above $250
- Same-day dispatch before 2pm CST
Laboratory research material only, not for human consumption. FOXO4-DRI holds no marketing authorisation in any market and has never been administered in a registered human trial. Affiliate links: we may earn a commission at no additional cost to you. Figures checked September 2, 2026.
FOXO4-DRI price against assayed content
The list price, current price and discounted price are unambiguous. What they buy is not.
Applying the assayed figures rather than the label produces a range rather than a number, and the range is wide enough to change a purchasing comparison.
| Basis | Net content | At $134.00 | At $67.00 |
|---|---|---|---|
| Kovera batch 55-05260628 | 11.41 mg | $11.74/mg | $5.87/mg |
| Label assumption | 10 mg | $13.40/mg | $6.70/mg |
| MZ Biolabs lot 55-01260229 | 8.30 mg | $16.14/mg | $8.07/mg |
Why purity does not rescue the calculation
A reasonable objection is that purity should correct the figure: if a vial is 99% pure, surely the mass is nearly all peptide.
That reasoning conflates two independent measurements. Purity describes what fraction of the material present is the target compound. Net content describes how much material is present at all. A vial containing 8.30 mg of 99.97% pure peptide contains 8.30 mg of peptide, not 10 mg.
Both published batches scored above 99% on purity. Purity was never the variable. Fill was, and fill is what per-milligram cost depends on.
What a quantitative assay actually involves
Net content is not read off a balance. It is determined by quantitative assay: the sample is dissolved, separated by HPLC, and the peak area compared against a reference standard of known concentration.
That method has its own uncertainty, and a certificate reporting 11.41 mg is reporting a measurement with a confidence interval rather than an exact count of molecules. The point is not that either figure is precisely right, but that both are measurements and the label is not.
MZ Biolabs reported its analysis as HPLC-UV-MS, combining separation, ultraviolet quantification and mass identification in one workflow. Kovera reported purity, net content, identity by LC-MS, endotoxin and sterility as separate line items.
The pricing question this does not answer
Whether $67.00 is a reasonable price depends on what the compound is worth, and that is not a documentary question.
FOXO4-DRI has no approved indication, no established human dose and no registered clinical trial. Its efficacy evidence is entirely preclinical: mice, rats and cultured cells. A compound in that position has no established value, only a market price.
There is also a documented risk that any valuation should weigh. A 2023 study reported that clearing senescent cells could promote pulmonary hypertension development and progression, so the expected benefit is not merely unproven but plausibly signed in either direction.
Frequently asked questions
- How much does FOXO4-DRI cost?
- A 10 mg vial lists at $199.99, currently sells at $134.00, and comes to $67.00 with the code. At the labelled mass that is $6.70 per mg.
- Why does cost per milligram vary between batches?
- Because measured net content varies. The two published certificates recorded 11.41 mg and 8.30 mg against the same 10 mg label, putting real cost at roughly $5.87 or $8.07 per mg.
- Does high purity mean a full vial?
- No. Purity and net content are independent measurements. Both published batches exceeded 99% purity while differing by 3.11 mg in actual content.
- How is net content measured?
- By quantitative assay: the sample is separated by HPLC and its peak area compared against a reference standard of known concentration. It is a measurement with uncertainty, unlike the printed label which is a claim.
Limitations of the evidence
This guide analyses pricing against published assay data from two batches only. Batch-to-batch variance beyond those two lots is unknown, and no inference about future batches is warranted. Nothing here bears on whether the compound has any effect in humans, which remains untested.
References
Citations are annotated with an evidence tier reflecting study design and replication. See Methodology for criteria.
- 1.Baar MP, Brandt RMC, Putavet DA, et al. · Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging · Cell · 2017PMID 28340339Preclinical
- 2.Circulation · Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression · Circulation · 2023PMID 36515093Preclinical